Lysoveta® LPC Omega-3
I took standard fish oil for years. I told my patients to take fish oil. I was wrong — not about omega-3, but about the form. Most omega-3 supplements never reach your brain in meaningful amounts.
Lysoveta uses the LPC form — the same carrier your brain's preferred transport system (Mfsd2a) is built for. The Alzheimer's Drug Discovery Foundation notes it offers "preferential benefits for ApoE4 carriers." 6x better brain absorption than standard fish oil.
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APOE4 Supplement Protocol
The Foundation Stack
Every APOE4 carrier should start here. These four supplements address the core biological vulnerabilities of the APOE4 genotype — and they're the foundation Jess builds every personalized protocol on top of.
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The APOE4 Foundation Stack
These five supplements are the non-negotiables — the baseline every APOE4 carrier should have in place before adding anything else. Click any card to expand the science, dosing, and Jess's personal note.
A Note for Caregivers
If you're here because someone you love has dementia and you're searching for anything that might help — I see you. I spent 30 years at the bedside with families in exactly that position. I want to be honest with you, because you deserve honesty more than you deserve false hope.
The research on Lysoveta omega-3 is primarily prevention and early intervention data. For someone already showing significant cognitive decline, the evidence for any omega-3 supplement producing noticeable improvement is modest. It won't harm them — and it's still far better than cheap fish oil — but I won't tell you it's going to reverse what's already happened. It isn't. I won't take your money on that promise.
Where it matters most is earlier. If your loved one is in the early stages, or if you're a known APOE4 carrier who watched a parent go through this and you're determined not to repeat it — that's exactly who this is designed for. The prevention window is real, and it's open longer than most people think.
If you're buying this for yourself because you're scared — good. That fear is information. Use it. And if you want to talk through where your loved one actually is in that window, that's exactly what my free evaluation is for.
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The APOE4 Specialty Stack
The foundation stack gets you started. The specialty stack is where we get specific — targeting neuroinflammation, vascular health, mitochondrial function, and advanced neuroprotection. Enter your email below to unlock Jess's full advanced protocol.
Curcumin Protocol (Upstream & Downstream)
Two-tier neuroinflammation strategy with dosing guidance
Omega-3 for Non-APOE4 Family Members
What to recommend for the non-carriers in your household
Advanced Tocotrienol Protocol
Neuroprotective tocotrienols beyond the foundation Gamma E
Vascular Support Stack
L-Citrulline + targeted compounds for cerebrovascular function
Mitochondrial Support
ALCAR + targeted energy compounds for APOE4 neurons
Senolytic Protocol
Fisetin-based cellular cleanup strategy
Unlock the Specialty Stack
Enter your name and email to get free access to Jess's advanced APOE4 supplement protocols — including the curcumin two-tier strategy, tocotrienol protocol, and more.
Why I recommend what I recommend: Every supplement on this page is something I personally use or have vetted with my clients over 30 years of dementia care. I include honest caveats, explain the APOE4 science behind each choice, and disclose all affiliate relationships. Some links earn a small commission at no extra cost to you — this is how I keep this resource free. Read my full recommendation philosophy →